Pharmacogenomic considerations in a pretransplant statin tolerant, post-transplant intolerant liver transplant patient: A case report

Michael J. Schuh

Mayo School of Health Related Sciences

https://orcid.org/0000-0003-0524-746X

DOI: https://doi.org/10.24926/iip.v17i1.6824

Keywords: liver transplant, pharmacogenomics, PGx, statin therapy, myalgias


Abstract

As pharmacogenomics testing is becoming more common, it can be used in more medical settings to assist in clinical decision making. This is a case study examining the implications of a patient having potentially different cytochrome P-450 enzyme phenotypes in the donor liver once transplanted. This patient tolerated statin therapy prior to liver transplantation but was intolerant to the same statin after liver transplant.

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