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2017-04-11
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Pharmacy Practice & Practice-Based Research
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Atypical Antipsychotic-Induced Parkinsonism: A Patient Case with CYP Enzyme Implications
Carla Dolci Figura
University of Florida
Michael Schuh
University of Florida
DOI: https://doi.org/10.24926/iip.v8i2.507
Keywords: Drug-induced Parkinsonism, Parkinsonism, Neuroleptic Medication, Medication Therapy Management, Pharmacotherapy
Abstract
Objective: To report a case of Parkinsonism potentially caused by neuroleptic medications.
Summary: The case analyzed is that of a 57-year-old male patient referred to a pharmacotherapy service by a neurologist after organic causes of tremor had been ruled out. Iatrogenic cause was suspected and referral expectation was to identify the offending agent or agents and propose alternative therapy.
Conclusion: This case illustrates iatrogenic risk associated with neuroleptic medications while illustrating mechanisms of drug interaction via CYP enzymes that can lead to iatrogenic disease.
Abbreviations: DIP = Drug-induced Parkinsonism; MTM = Medication Therapy Management; PD = Parkinson’s Disease
Type: Clincial Experience
