pdf
Published
2022-04-07
Issue
Section
Pharmacy Practice & Practice-Based Research
Categories
License
Copyright (c) 2022 W. Anthony Hawkins, Aliya Abdulla, Xiaodong Hua, Andrea Sikora
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright of content published in INNOVATIONS in pharmacy belongs to the author(s).
Sedative Choice: The Chilling Confounder to Targeted Temperature Management
W. Anthony Hawkins
University of Georgia College of Pharmacy
Aliya Abdulla
University of Georgia College of Pharmacy
Xiaodong Hua
Augusta University
Andrea Sikora
University of Georgia College of Pharmacy
DOI: https://doi.org/10.24926/iip.v13i1.4501
Keywords: analgesics, physician prescribing, medication safety, CPR, critical care
Abstract
Targeted temperature management (TTM) is a technique used in adults who lack a meaningful response after the return of spontaneous circulation following cardiac arrest (CA). The implementation of TTM is believed to improve neurological outcomes by decreasing cerebral metabolism, reducing apoptosis, and lowering oxygen demand. While this technique is recommended as a part of advanced cardiovascular life support (ACLS), there is a lack of consistency regarding drug choice and depth of sedation in TTM. In this report, the authors provide a review of the myriad of regimens outlined in research protocols and current guidelines to stimulate discussion and promote further studies pertaining to sedation strategies in TTM. Through this call to action, the ultimate goal is to develop a uniform approach to bedside practice.
