Impact of a Pharmacist-Led Warfarin to Direct Oral Anticoagulant Conversion Initiative during the COVID-19 Pandemic

Kelsey Mews

Mayo Clinic Health System

Audrey Umbreit

Mayo Clinic Health System

Emily Holm

Mayo Clinic Health System

Kelsie Davis

Mayo Clinic Health System

Ellen Kelly

Mayo Clinic Health System

Carson Reinhardt

Mayo Clinic Health System

Allison Young

Mayo Clinic Health System

Joseph Flynn

Mayo Clinic Health System

DOI: https://doi.org/10.24926/iip.v13i1.4491

Keywords: DOAC, COVID-19, anticoagulation


Abstract

Purpose: To assess the impact of a pharmacist-led warfarin to DOAC conversion initiative during the COVID-19 pandemic.

Methods: Patients who were prescribed warfarin and followed with the anticoagulation clinic for INR monitoring were assessed by outpatient clinical pharmacists as potential candidates for transition to DOACs from March-August 2020.

Results: 530 patients were assessed for transition to DOACs, of which 373 (70.4%) were deemed by clinical pharmacists to be candidates for DOACs.  Of the patients who were candidates for DOACs, 66 (17.7%) were transitioned from warfarin to a DOAC.  Of the patients who transitioned to a DOAC, 59 (89.4%) remained on a DOAC after one year.

Conclusion: Outpatient clinical pharmacists are an effective resource to help identify patients who are candidates for DOACs and assist with transition from warfarin. Further, high persistence rates with DOAC therapy after one year demonstrate the positive impact of the clinical pharmacist on medication adherence.

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