Antifungal Drugs Shortage in India amidst Looming Increase in Invasive Fungal Infections among COVID-19 Patients: An Impending Crisis

  • Behram Khan Ghazi Punjab Medical College, Faisalabad, Pakistan; Faisalabad Medical University, Faisalabad, Pakistan
  • Usman Zahid Punjab Medical College, Faisalabad, Pakistan; Faisalabad Medical University, Faisalabad, Pakistan
  • Muhammad Abdullah Usman Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan
  • Zohra Kazmi Jinnah Medical and Dental College, Karachi, Pakistan
  • Reem Hunain Kasturba Medical College, Manipal, India
  • Mehr Muhammad Adeel Riaz Punjab Medical College, Faisalabad, Pakistan
  • Osman Kamal Osman Elmahi Faculty of Medicine, Ibn Sina University, Khartoum, Sudan
  • Mohammad Yasir Essar Kabul University of Medical Sciences, Kabul, Afghanistan
  • Mohammad Mehedi Hasan Mawlana Bhashani Science and Technology University, Tangail, Bangladesh
Keywords: Antifungal drugs, shortage, India, mucormycosis, Government policy

Abstract

The widespread prevalence of fungal infections in the second wave of COVID-19 pandemic could be owed to ubiquitous and injudicious use of steroids and immunosuppressive nature of the virus. However, these fungal infections also meant increased use of antifungal drugs, hence endangering their supply. Amphotericin B is the first line drug for mucormycosis which was declared as an epidemic in India during the second wave. With the increasing demand of the drug, came challenges to manufacture and supply large quantities of the drug and exploitation by creating a black market and spread of false information and imprudent usage. It is of utmost importance to be prepared with adequate supply all over the nation and implementing safety regulations in manufacturing and supply of large quantities of drugs during the demanding times and make them accessible at a reasonable rate.

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Dates
Received 2021-11-28
Accepted 2022-04-22
Published 2022-05-25
Section
Pharmacy Practice & Practice-Based Research